Overview of Potential SARS-CoV-2 Vaccine Platforms

It may take years to develop a vaccine for human use, especially if the new technology currently in use has not yet undergone extensive safety testing or mass production. There is currently no coronavirus vaccine on the market and no large-scale vaccine production capacity. The first vaccine development process can be lengthy and time-consuming.

Moderna and the Vaccine Research Center at the National Institutes of Health jointly developed an mRNA vaccine. The mRNA is encapsulated in lipid nanoparticles and injected into the body to express the target antigen in the body. This is currently the furthest along, and a phase I clinical trial recently started (ClinicalTrials .gov: NCT04283461). Curevac is developing a similar vaccine, but it is still in the preclinical phase.